Toxic psychosis due to chloroquine overdose: a case report.

Malaria is an endemic disease in developing countries like India. Peripheral smear examination for malarial parasites, though the gold standard for diagnosis is observer-dependent and may be reported as negative even in strongly-suspected cases. Hence, a large number of patients having fever are empirically treated with antimalarial drugs. Chloroquine and its derivatives have been the drugs of choice in the prophylaxis and treatment of uncomplicated malaria for over many years. Common side-effects of chloroquine are nausea, vomiting and unpleasant taste. Central nervous system adverse events following chloroquine have been described1–4. We herein report a child who developed psychosis following chloroquine overdose.